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BHAISHAJYA KALPANA
PAPER-I
Adharabhuta Siddhant and Pharmacy Management
PART-A
Adharabhuta Siddhant
Concept of Bheshaja and Kalpana, difference between Aushadh and Bheshaj, History and Chronological evaluation of Bhaishajya kalpana. Knowledge about classical texts related to Bhaishajya kalpana with special emphasis on Bruhatrayi, Sharangdhar Samhita, Chakradatta, Bheshaj Kalpa, Bhaishajya Ratnavali, Bhava Prakash Nighantu, Vaidyaka Paribhasha Pradipa,
 
Fundamental Principles of Bhaishajya kalpana and Rasa shastra including principles of designing different formulations with reference to Samslesha Vishleha and other principles.
 
Study of ancient and metric systems of weights and measures including Kala mana with their correlation.
 
Technical terminologies (Paribhasha) used in Bhaishajya kalpana and Rasa shastra
 
Collection, Storage and Preservation methods of different Fresh and Dry Aushadhi dravyas, their Grahya Agrahyatva
 
Detailed knowledge of  Dose, Anupana, Aushadha sevan kala and Route of Drug Administration
 
Ancient view of Aushadha nirmana shala and Ayurvedic pharmacy in accordance with GMP.
 
 
PART- B
 
Pharmacy Management
 
Management of Pharmacy, Store and Inventory Management, Personnel Management, Good Manufacturing Practices related to Ayurvedic Drug Industry.
 
Marketing Pharmaceutical Services
 
Product Release and Withdrawals
 
Community Pharmacy
 
Laws Governing Pharmacy
 
Relevant regulatory provisions of Ayurvedic drugs in Drug and Cosmetic Act 1940 and Rules 1945
Laws pertaining to Drugs and Magic remedies (objectionable advertisement) Act-1954.
Prevention of Food Adulteration (PFA) act.
4. Laws pertaining to Narcotics
Factory and Pharmacy Acts
Consumer Protection Act -1986
  
Regulatory Affairs related to International Trade and Practices of Ayurvedic Drugs
 
Introduction to Ayurvedic Pharmacoepia of India, Ayurvedic Formulary of India.
 
Introduction to Indian Pharmacoepia, British and United States Pharmacoepia, Pharamcoepial Codex
 
Introduction to Traditional Knowledge Digital Library
 
 
PAPER-II
 
Aushadha Prasamsaskarana
 
PART-A  
 
Detailed ancient & contemporary knowledge with Pharmacognostical/ Geochemical/Mineralogical identification, source, occurrence, availability, classification, physico-chemical characterization, grahya-agrahyatva, therapeutic properties and uses of raw material of plant, mineral and animal origin. 
 
Detailed knowledge of ancient and contemporary Yantropakarana and their accessories used in Aushadhikaran and their contemporary modification such as  Khalva yantras, Peshani Yantra, Pulveriser, Disintegrator, Sieve Shaker, Tableting Machine, Pill thread making and Pill cutting Machine, Mixer, Mass Mixer, Grinder, Emulsifier,   Strip/ Blister Packing Machine, Bottle sealing, Pouch packing Machine, Ointment Making Machine,  Chullika, Koshthis, Bhrashtris, and other heating appliances, Svedan Yantra, Ovens, driers etc. used in manufacturing of small scale and large scale manufacturing of Ayurvedic Formulations along with their applications.
 
Study of Samskara, definition, types and its effect on Physico- chemical and Therapeutic properties of Samskararha dravya.
Role of Agni (Heat), Jala and other dravas (Water and other processing liquids), Kala (Time span), Patra (Container) and other processing materials and their significance in Aushadhikaran.
  
Study of Mardana and its significance in Aushadhikaran. Concept of Bhavana, detailed knowledge of ancient and contemporary grinding and trituration techniques.
 
PART –B
 
Detailed Knowledge of Concept, Standard Operating Procedure of manufacturing, Standardization, Quality control, Storage, Technological development in processing and modification in following dosage forms in relation to their usage and acceptability.
 
Panchavidha Kashaya, Satva, Nisyand, Kshira, Sara, Kshara, Arka, Lavana, Ushnodaka, Aushadha Siddha Udaka, Pramathya, Panaka, Mantha, Tarpana, Saktu
 
Curna, Gutika, Vatika, Modaka, Guggulu, Varti
 
Pathya Kalpana
 
Sneha Kalpana
 
Sandhan kalpana
 
Bahya Prayogartha Kalpana
 
Lepa, Upanaha, Malahara, Udvartan, Avadhupan, Abhyanga
 
Dhupan and Dhumrapan
 
Mukha, karna, Nasa and Netra Kalpana
 
Basti Kalpana
 
 
PAPER –III
 
Aushadha Yoga Vigyan
 
 
PART –A
  
Bhaishajya Yoga Vigyan
  
Detailed knowledge of Aushadhi Path Samyojana, Therapeutic efficacy, Mechanism of action, Dose, Anupan and Method of administration of following Aushadhi Yogas:
  
Panchavidha Kashayas and their Upakalpa
 
Ardraka swarasa, Tulasi swarasa, Vasa putapaka swarasa, Nimba kalka, Rasona kalka, Kulattha Kwath, Punarnavasthaka kwatha, Rasna saptaka kwatha, Dhanyak hima, Sarivadi hima, Panchakola phanta, Mustadi pramathya, Kharjuradi mantha, Shadanga paniya, Laksha rasa, Ajamoda arka, Yavanyadi arka, Chincha panaka, Candana panaka, Banapsha sharkara, Nimbu sarkara, Darvi rasakriya, Amrita satva, Ardraka satva, Arjuna kshirapaka, Rasona kshirapaka,
 
 Pathya Kalpana – Yavagu, (Krita and Akrita), Ashtaguna manda, Laja manda, Peya, Vilepi, Krishara, Yusha,  Mudga yusha, Kulattha yusha, Saptamushtika yusha, Khad, Kambalika, Raga, Shadava Mamsarasa, Veshavara,  Takra, Udasvita, Katvar, Mathita, Chhacchika, Dadhi, Tandulodaka, Neutraceuticals and Food Supplements
Churna
Sitopaladi Churna, Talisadi Churna, Triphala Churna, Hingvashtaka Churna, Yashtimadhu Churna, Avipattikara Churna, Swadishta Virechana Churna, Trimada Virechana Churna,
 
Lavana Bhaskar Churna, Sudarshana Churna, MahaSudarshana Churna, Gandharva Haritaki Churna, Navayasa Churna, Pushyanuga Churna, Ajamodadi Churna, Hingvadi Churna, Eladi Churna, Dadimashtaka Churna, Trikatu Churna, Vaishwanara Churna
 
Gutika
Arogya vardhani vati, Chandraprabha vati, Chitrakadi Gutika,, Sanjivani Vati, Lasunadi vati, Lavangadi Vati, Vyoshadi vati, Khadiradi Vati,  Kankayan Vati, Abhayadi modak, Marichyadi gutika, Amalakyadi gutika, Samshamini Vati, Kutaja Ghana vati

Guggulu

 
Yogaraja Guggulu, Maha yogaraja Guggulu, Trayodashanga Guggulu, Kanchanara Guggulu, Rasnadi Guggulu, Triphala Guggulu, Simhanada Guggulu, Gokshuradi Guggulu, Kaishora Guggulu, Panchatikta Guggulu, Amritadi Guggulu, Vatari Guggulu, Lakshadi Guggulu, Abha Guggulu
 
Snehapaka
 
Sneha Moorchhana - Ghrita Murchana, Taila Murchhana
 
Siddha Ghrita-  Shatavari Ghrita, Jatyadi Ghrita, Phala Ghrita, Dadimadi Ghrita, Kshira Shatpala Ghrita, Triphala Ghrita, Dhanvantri Ghrita, Amritaprasha Ghrita, Kalyanaka Ghrita, Brahmi Ghrita, Changeri Ghrita, Panchatikta Ghrita, Sukumara Ghrita
 
Siddha Taila - Maha Narayana Taila, Maha Masha Taila, Bala Taila, Nirgundi Taila, Shadbindu Taila, Vishagarbha Taila, Sahacharadi Taila, Jatyadi Taila, Apamarga Kshara Taila,Tuvaraka Taila, Kshirabala Taila, Lakshadi Taila, Anu Taila, KumKumadi Taila, Hingutriguna Taila, Kottumchukadi Taila, Prasarinyadi Taila, Dhanwantari Taila, Balashwagandhadi Taila, Balaguduchyadi Taila, Nilibhringyadi Taila,  Brihadavadi Taila, Irimedadi Taila, Chandanadi Taila, Panchaguna taila, Arka taila
 
 
Avaleha
 
Vasa Avaleha, Brahma rasayana, Chyavanprasha Avaleha, Kushmanda Avaleha, Vyagri Haritaki Avaleha, Dadima Avaleha, Bilvadi Avaleha, Kantakaryavaleha, Haridra Khanda, Narikela khanda, Saubhagya shunthi paka.
 
7.Sandhan Kalpa
 
Shukta- Ikshu shukta, Tushambu, Kanjik, Sandaki
 
Madya - Sura, Shidhu, Varuni
 
Asava Arishta - Lodhrasava, Kumaryasava, Ushirasava, Chandanasava, Kanakasava, Sarivadyasava, Pippalyasava, Lohasava, Vasakasava, Kutajarishta, Draksharishta, Raktamitrarka, Dashamularishta, Abhayarishta, Amritarishta, Ashokarishta, Sarasvatarishta, Arjunarishta, Khadirarishta, Ashwagandha Arishta, Vidangarishta, Takrarishta.
 
Miscellaneous - Phala varti, Chandrodaya varti, Arka lavana, Narikela lavana, Triphala masi, Apamarga kshara, Snuhi kshara, Ksharasutra, Atasi upanaha, Sarjarasa malahara, Gandhaka malahara,Sinduradi Malahar, Shatadhouta Ghrita, Sahasra Dhouta Ghrita, Sikta taila, Dashanga lepa, Doshaghna lepa,  Bhallataka taila, Jyotishmati Taila, Bakuchi Taila, Dashanga dhupa, Arshoghna dhupa, Nishadi Netra bindu, Madhutailika Basti, Sneha Basti, Matra Basti, Yoga Basti, Karma Basti, Kala Basti.
 
PART- B
 
Rasa Yoga Vigyan
 
Detailed knowledge of Aushadhi Patha Samyojan, Therapeutic efficacy, Mechanism of action, Dose, Anupan and Method of administration of following Aushadhi Yogas
 
Kharaliya Yoga
 
Shwasakuthara Rasa, Tribhuvanakirti Rasa, Higuleshwara Rasa, Anandabhairava Rasa, MahaLakshmivilasa Rasa, Vasnathakusumakara   Rasa, Vasantamalti Rasa, Bhrihatvata chintamani Rasa, Laghusutashekhar Rasa, Sutashekhar Rasa, Ramban Rasa, Chandrakala Rasa, Yogendra Rasa, Hridyarnava rasa, Grahanikapata Rasa, Garbhapala Rasa, Jalodarari Rasa, Mrityunjaya Rasa, Madhumalini vasanta Rasa, Arshakuthara Rasa, Krimimudgara Rasa, Suchikabharana Rasa, Trinetra Rasa, Smrutisagara Rasa, Vatagajankusha Rasa, Agnikumar Rasa, Ekangavir Rasa, Kamadudha Rasa, Purnachandrodaya Rasa, Prataplankeshwara Rasa, Mahavata vidhwansaka Rasa, Kasturibhairava Rasa, Ashwakanchuki Rasa, Gulmakuthara Rasa, Mahajwarankusha Rasa, Chandramrita Rasa, Kaphaketu Rasa, Prabhakara Vati, Pravala Panchamrita, Gandhaka Rasayana, Chaturbhuj rasa, Navajivan rasa, Shonitargal rasa, Raktapitta kulakandan rasa, Amavatari Rasa, Kravyada Rasa, Garbhachintamani Rasa, Chintamani Rasa, Trilokyachintamani Rasa, Pradarantaka Rasa, Vangeshwara Rasa, Brihatvangeshwara Rasa, Shwasakasa Chintamani Rasa, Smritisagar Rasa, Arogyavardhini Vati, Chandraprabha Vati, Agnitundi vati, Shankha Vati.
 
Loha Kalpa
 
Ayaskriti, Loha Rasayana, Amlapittantaka loha, Chandanadi loha, Dhatri loha, Navayasa loha, Putapakva vishamajwarantaka loha, Shilajatwadi loha, Tapyadi loha, Saptamrita loha, Amlapittantaka loha, Chandanadi loha, Dhatri loha, Punarnava Mandura, Amritasara Loha, Shankaramat loha, Pradarantaka loha, Rohitaka loha.
 
Kupipakva Yoga
 
Rasa Sindura, Makaradhwaja, Sidhamakaradhwaja, Samirapannaga Swarnavanga, Malla sindura, Rasa karpura, Rasa pushpa, Manikya Rasa.
 
Parpati Yoga
 
Rasa Parpati, Loha Parpati, Tamra Parpati, Suwarna Parpati, Gagana Parpati, Vijay Parpati, Panchamrit Parpati, Shwet Parpati, Bola Parpati .
 
Pottali Yoga
 
sagarbhapottali, Hemagarbhapottali, Mallagarbha pottali,  pottali, Hiranyagarbha pottali, Shankagarbha pottali, Lokanatha rasa, Mriganka Pottali.
 
PAPER - IV
 
Pharmaceutical Science
 
PART - A
 
Pharmaceutical technology
  
Scope and Evolution of Pharmacy
 
Information Resources in Pharmacy and Pharmaceutical Science
 
Posology
 
Colloidal and Coarse dispersion and Pharmaceutical Rheology
 
Preformulation
 
Separation
 
Principles of Distillation, Methods of Extraction, Infusion, Decoction, Maceration, Percolation and Fusion
 
Sterilization & Sterile products, Ophthalmic and Parenteral Preparations
 
Preservation and stabilization of pharmaceutical products
 
Drying, Open and Closed Air drying, Freeze drying, Vacuum drying and other drying methods
 
Pharmaceutical Excipients
 
Oral Solid Dosage Forms, Powder,   Size reduction & size separations,    Principles of mixing Micrometrics- Methods of determination of particle size, shape & Surface area, Methods of compression & Consolidation of powder solids
 
Tablets, Sustained release dosage forms, Suppositories & Pessaries
 
Capsules- Hard capsules & soft gelatin capsules & micro incapsulation

Semisolid Dosage Forms Emulsion, Suspensions and Extracts
 
Liquids - Solution, Solubility Phenomenon, Diffusion & Dissolution, pH, Buffers & Isotonic solutions, Clarification & Filtration Techniques of filtration & Centrifugation, Syrup, Elixirs
 
Pharmaceutical aerosols
 
Topical drugs and Cosmetics
 
Packaging Materials and Labeling
 
Standardization of Raw material, In process Material and Finished Product
 
 
PART – B
 
Pharmacology & Toxicology
Pharmacology
 
Principles of Pharmacology
 
Pharmcodynamics & Pharmacokinetics: Absorption, distribution, mechanism of action & Excretion, Dose response relationship, structure activity relationship
 
Routes of administration of drug
 
Factors modifying drug effect, Drug interactions, Adverse drug reaction and Drug toxicity
 
Detailed Knowledge of Pharmacovigilance – National and International Scenario. Pharmacovigillance of Ayurvedic Drugs
 
Clinical pharmacology: Preclinical & clinical evaluation, Bioavailability and Bioequivalence
 
Toxicology
 
Principles of Toxicology
 
Toxicology of Metallic, Mineral, Plant & Animal products
 
General principles of Management of Acute and Chronic Toxicity
 
Practicals
 
[Minimum 150 practicals to be performed covering all the dosage forms.
 
Educational Visits to minimum Five(5) GMP approved Ayurvedic Pharmacies
 
Ten days posting in R&D / Production unit in Ayurvedic Pharmacy.
 
Reference Books
 
Relevent parts of Charak, Sushrut, Vagbhata and Sharngadhar
 
Bheshaj Kalpa
 
Bhavaprakash
 
Siddha Bhaishajya Manimala
 
Bhaishajya Ratnavali
 
Ayurvediya Aushadhikarana                – Puranika and Dhamanakar
 
Rasa Bhaishajya Kalpana Vigyan                             – Santosh Khandal
 
Bharat Bhaishajya Ratnakar
 
Vaidyaka Paribhasha Pradeepa
 
Kriyatmak Aushadhi Parichaya Vigyan
 
Ayurvedeeya Aushadhikarana                       – Puranika and Dhamanakar

 
Dravyaguna Vijnan Pat-1 and 2                 - Yadavji Trikamji Acharya
 
Dravyaguna                               – Chakradatta   CCRAS Publication
 
Remington: Science and Practice of Pharmacy
 
Industrial Pharmacy                                                    – Lackman
 
Text Book of Phrmacology                           – Goodman and Gilman
 
Data Base of Medicinal Plants                           – CCRAS Publication
 
Quality and Standards of Medicinal Plants            – ICMR publication
 
Quality Control of Ayurvedic Drugs         – PLIM, Gaziabad publication
 
Ayurvedic Pharmacopeia of India
 
Ayurvedic Formulary of India
 
Indian Pharmacopeia
 
British Pharmacopeia
 
United States Pharmacopeia
 
Pharmacopeia Codex
 
Current Good Manufacturing Practices
 
Drugs and Cosmetic Act 1940 and Rules 1945
 
Drugs and Magic remedies (Objectionable advertisement) Act-1954
 
Prevention of Food Adulteration (PFA) act
 
Laws pertaining to Narcotics
 
Factory and Pharmacy Acts
 
Consumer Protection Act -1986
 
Siddha Yoga Samgriha                          –Yadavaji Trikamji Acharya
 
Sahasrayoga

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